UCP1 (Mitochondrial Brown Fat Uncoupling Protein 1, Uncoupling Protein 1 (Mitochondrial, Proton Carrier)), Rabbit
Catalog Number:
USB-495119
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| Article Name: | UCP1 (Mitochondrial Brown Fat Uncoupling Protein 1, Uncoupling Protein 1 (Mitochondrial, Proton Carrier)), Rabbit |
| Biozol Catalog Number: | USB-495119 |
| Supplier Catalog Number: | 495119 |
| Alternative Catalog Number: | USB-495119-100 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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