MRP2 (Multidrug Resistance-associated Protein 2, ABC30, ATP-binding Cassette Sub-family C Member 2, ATP-binding Cassette Sub-family C (CFTR/MRP) Member 2, ABCC2, Canalicular Multidrug Resistance Protein, CMRP, Canalicular Multispe
Biozol Catalog Number:
USB-M4688-20B
Supplier Catalog Number:
M4688-20B
Alternative Catalog Number:
USB-M4688-20B-1
Manufacturer:
US Biological
Host:
Mouse
Category:
Antikörper
Application:
FC, IHC, WB
Immunogen:
Bacterial fusion protein corresponding to aa215-310 of human MRP2.
MRP2 is a 170-180kD transmembrane protein known as the canalicular multi-organic anion transporter, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. MRP2 is closely related to the multidrug resistance related protein MRP, and MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. Has potential value for detection of MRP2-mediated drug-resistance in human tumor samples. Applications: Suitable for use in Flow Cytometry, Immunocytochemistry, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: Immunohistochemistry (Acetone fixed frozen): 1:20 Immunocytochemistry: 1:20-1:50 on acetone fixed cytospin preparations. Western Blot: 1:20-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality:
Monoclonal
Clone Designation:
[M21-4]
Isotype:
IgG1
Purity:
Supernatant
Form:
Supplied as a liquid, 0.7% BSA, 0.09% sodium azide.
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