Anti-DR5 [YSd1], Human IgG1, kappa, Monoclonal
Catalog Number:
ABA-AB00915-10.0
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| Article Name: | Anti-DR5 [YSd1], Human IgG1, kappa, Monoclonal |
| Biozol Catalog Number: | ABA-AB00915-10.0 |
| Supplier Catalog Number: | Ab00915-10.0 |
| Alternative Catalog Number: | ABA-AB00915-10.0 |
| Manufacturer: | Absolute Antibody |
| Host: | Human |
| Category: | Antikörper |
| Application: | NTRL |
| Species Reactivity: | Human |
| Alternative Names: | TRAILR2, Death receptor 5, DR-5, TRAIL receptor 2, Tumour necrosis factor receptor superfamily member 10B, TNFRSF10B |
| Fab fragments were generated by constructing phage-display libraries in which the CDRs of a humanised Fab framework derived from the murine Ab 4D5 were randomised (see Eigenbrot et al, 1993). The 1st and 2nd CDRs of the VH domain were replaced by randomised sequences consisting only of Tyr and Ser residues, whilst the 3rd VH CDR was substituted with random loops of variable lengths comprising all naturally occurring amino acids. Specific Fabs were isolated using ELISA screening. |
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