Anti-GITR [DTA-1], Rat IgG2a, lambda, Monoclonal

Product Overview

• Article Name: Anti-GITR [DTA-1], Rat IgG2a, lambda, Monoclonal
• Biozol Catalog Number: ABA-AB01060-7.1-BT
• Supplier Catalog Number: Ab01060-7.1-BT
• Alternative Catalog Number: ABA-AB01060-7.1-BT
• Manufacturer: Absolute Antibody
• Host: Rat
• Category: Antikörper
• Application: FC, Functional Studies, IP, WB
• Species Reactivity: Mouse
• Alternative Names: CD357, AITR, GITR-D, Glucocorticoid-induced TNFR-related protein, TNFRSF18, Tumor necrosis factor receptor superfamily member 18

Product Description

This antibody was raised by immunising Wistar rats with the CD25+CD4+ T cell line. Hybridoma cells were generated by fusing spleen cells from the immunized rat with P3X63Ag8.653 myeloma cells, assessed for secreting antibodies capable of neutralizing in vitro CD25+CD4+ T cell-mediated suppression of anti-CD3-stimulated T cell proliferation9, and then cloned. This DTA-1 clone secreted a monoclonal rat immunoglobulin G2a (IgG2a) that showed high neutralizing activity.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [DTA-1]
• Isotype: IgG2a
• UniProt: O35714
• Buffer: PBS only.
• Source: Rat
• Target: GITR
• Antibody Type: Recombinant Antibody