Anti-CCL11 [CAT-213 (Bertilimumab, iCo-008)], Human IgG1, Fc Silent(TM), kappa, Clone: [CAT-213 Bertilimumab, iCo-008], Monoclonal

Catalog Number: ABA-AB04187-10.3-BT
Article Name: Anti-CCL11 [CAT-213 (Bertilimumab, iCo-008)], Human IgG1, Fc Silent(TM), kappa, Clone: [CAT-213 Bertilimumab, iCo-008], Monoclonal
Biozol Catalog Number: ABA-AB04187-10.3-BT
Supplier Catalog Number: Ab04187-10.3-BT
Alternative Catalog Number: ABA-AB04187-10.3-BT
Manufacturer: Absolute Antibody
Host: Human
Category: Antikörper
Application: ELISA, FA, NeA
Species Reactivity: Human
Alternative Names: SCYA11, Eotaxin, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11, 3G3
The original scFv antibody 3G3 was isolated from a human scFv phage display library after three rounds of panning against human eotaxin1. Optimization of 3G3 was conducted by heavy chain CDR3 randomization with point mutagenesis and light chain shuffling to obtain CAT-212 (scFv). Later on the sequence of CAT-212 was used to generate human IgG4 version of the antibody, which was called CAT-213.
Clonality: Monoclonal
Clone Designation: [CAT-213 Bertilimumab, iCo-008]
Isotype: IgG1
UniProt: P51671
Buffer: PBS only.
Target: CCL11