Anti-CCL11 [CAT-213 (Bertilimumab, iCo-008)], Mouse IgG2b, Fc Silent(TM), kappa, Clone: [CAT-213 Bertilimumab, iCo-008], Monoclonal

Product Overview

• Article Name: Anti-CCL11 [CAT-213 (Bertilimumab, iCo-008)], Mouse IgG2b, Fc Silent(TM), kappa, Clone: [CAT-213 Bertilimumab, iCo-008], Monoclonal
• Biozol Catalog Number: ABA-AB04187-3.3
• Supplier Catalog Number: Ab04187-3.3
• Alternative Catalog Number: ABA-AB04187-3.3
• Manufacturer: Absolute Antibody
• Host: Mouse
• Category: Antikörper
• Application: ELISA, FA, NeA
• Species Reactivity: Human
• Alternative Names: SCYA11, Eotaxin, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11, 3G3

Product Description

The original scFv antibody 3G3 was isolated from a human scFv phage display library after three rounds of panning against human eotaxin1. Optimization of 3G3 was conducted by heavy chain CDR3 randomization with point mutagenesis and light chain shuffling to obtain CAT-212 (scFv). Later on the sequence of CAT-212 was used to generate human IgG4 version of the antibody, which was called CAT-213.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [CAT-213 Bertilimumab, iCo-008]
• Isotype: IgG2b
• UniProt: P51671
• Buffer: PBS with 0.02% Proclin 300.
• Target: CCL11