CD220, HHF5, IR, HIR, INSR, HINSR, human insulin receptor monoclonal antibody, 83-14
This humanized antibody, based on the anti-insulin receptor alpha antibody clone 83-14 (Ab00137), was generated by grafting the complementarity-determining regions (CDRs) of the original murine IgG1 antibody onto the human B43 IgG1 heavy chain and the human REI kappa light chain frameworks.