TFE3 Rabbit mAb, Unconjugated

Catalog Number: ABB-A0548
Article Name: TFE3 Rabbit mAb, Unconjugated
Biozol Catalog Number: ABB-A0548
Supplier Catalog Number: A0548
Alternative Catalog Number: ABB-A0548-100UL,ABB-A0548-20UL,ABB-A0548-500UL,ABB-A0548-1000UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, IHC-P, WB
Species Reactivity: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: TFEA, RCCP2, RCCX1, MRXSPF, bHLHe33, TFE3
This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.
Clonality: Monoclonal
Clone Designation: [ARC1829]
Molecular Weight: 62kDa
NCBI: 7030
UniProt: P19532
Purity: Affinity purification
Sequence: LQQARRQQVKQYLSTTLGPKLASQALTPPPGPASAQPLPAPEAAHTTGPTGSAPNSPMALLTIGSSSEKEIDDVIDEIISLESSYNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLP
Target: TFE3
Antibody Type: Primary Antibody
Application Dilute: WB,1:1000 - 1:4000|IHC-P,1:100 - 1:400|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Cancer,Immunology Inflammation