ABflo 488 Rabbit anti-Human IL-17RB mAb, Monoclonal

Product Overview

• Article Name: ABflo 488 Rabbit anti-Human IL-17RB mAb, Monoclonal
• Biozol Catalog Number: ABB-A24315
• Supplier Catalog Number: A24315
• Alternative Catalog Number: ABB-A24315-100T,ABB-A24315-2X100T,ABB-A24315-5X100T
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: ABflo 488
• Alternative Names: IL17RB, CRL4, EVI27, IL17BR, IL17RH1, interleukin-17 receptor B

Product Description

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 31kDa/55kDa
• NCBI: 55540
• UniProt: Q9NRM6
• Purity: Affinity purification
• Target: IL17RB

Application Notes

• Application Dilute: FC,5 µl per 10 6 cells in 100 µl volume
• Application Notes: Cross-Reactivity: Human. ResearchArea: Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Immunology & Inflammation,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway. Shipping: Ice Bag

Images

Flow cytometry:1X10 6 MOLT-4 cells (negative control,Left)and HepG2 cells (Right) were surface-stained with ABflo 488 Rabbit anti-Human IL-17RB mAb(A24315,5 µl/Test,orange line) or ABflo 488 Rabbit IgG isotype control (A22069,5 µl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).