CCL5 Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A24848
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| Article Name: | CCL5 Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A24848 |
| Supplier Catalog Number: | A24848 |
| Alternative Catalog Number: | ABB-A24848-20UL,ABB-A24848-100UL,ABB-A24848-1000UL,ABB-A24848-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | C-C motif chemokine 5 |
| This gene is one of several chemokine genes clustered on the q arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immune regulation and inflammatory processes. According to the arrangement of N-terminal cysteine residues in mature peptides, the superfamily is divided into four subfamilies. This chemotactic factor belongs to the CC subfamily and is a chemotactic agent for blood monocytes, memory T helper cells, and eosinophils. It causes basophils to release histamine and activate eosinophils. This cytokine is one of the main HIV inhibitors produced by CD8+cells. It is one of the natural ligands of chemokine receptor chemokine receptor 5 (CCR5), which inhibits in vitro replication of HIV-1 R5 strains using CCR5 as a co receptor. Optional splicing leads to multiple transcriptional variants encoding different isomers. |
| Application Dilute: | WB,1:1000 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Rat. ResearchArea: Chemotaxis, Inflammatory response. Shipping: Ice Bag |
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Western blot analysis of lysates from Rat lung usingCCL5 Rabbit pAb (A24848) at1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
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