ABflo 647 Rabbit anti-Human Syk mAb, Monoclonal

Product Overview

• Article Name: ABflo 647 Rabbit anti-Human Syk mAb, Monoclonal
• Biozol Catalog Number: ABB-A25739
• Supplier Catalog Number: A25739
• Alternative Catalog Number: ABB-A25739-100T,ABB-A25739-2X100T,ABB-A25739-5X100T
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: ABflo 647
• Alternative Names: IMD82, p72-Syk

Product Description

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Clonality: Monoclonal
• Concentration: FC (intra)
• Molecular Weight: 72kDa/70kDa
• NCBI: 6850
• UniProt: P43405
• Purity: Affinity purification
• Target: SYK

Application Notes

• Application Dilute: FC (intra),5 µl per 10 6 cells in 100 µl volume
• Application Notes: Cross-Reactivity: Human. ResearchArea: Protein phosphorylation,Signal Transduction,Kinase,Tyrosine kinases,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,Immunology Inflammation,B Cell Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood. Shipping: Ice Bag

Images

Flow cytometry: 1X10 6 Human PBMC were surface-stained with FITC Mouse anti-Human CD19 mAb (A22815,5 µl/Test) followed by intracellular staining with ABflo 647 Rabbit anti-Human Syk mAb (A25739,5 µl/Test,left) or ABflo 647 Rabbit IgG isotype control (A22070,5 µl/Test,right).