Gasdermin B (Full Length+C terminal) Rabbit pAb, Unconjugated, Polyclonal

Product Overview

• Article Name: Gasdermin B (Full Length+C terminal) Rabbit pAb, Unconjugated, Polyclonal
• Biozol Catalog Number: ABB-A25770
• Supplier Catalog Number: A25770
• Alternative Catalog Number: ABB-A25770-100UL,ABB-A25770-20UL,ABB-A25770-1000UL,ABB-A25770-500UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: GSDML, PP4052, GSDMB-1, PRO2521, Gasdermin B (Full Length+C terminal)

Product Description

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.

Product Properties

• Clonality: Polyclonal
• Concentration: WB
• Molecular Weight: 18kDa/45kDa/46kDa/47kDa
• NCBI: 55876
• UniProt: Q8TAX9
• Purity: Affinity purification
• Sequence: SLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS
• Target: GSDMB

Application Notes

• Application Dilute: WB,1:500 - 1:1000
• Application Notes: Cross-Reactivity: Human. ResearchArea: Cell Biology, Developmental Biology. Shipping: Ice Bag

Images

Western blot analysis of lysates from 293T GSDMB stable cells and 293T GSDMB stable cells transfected with GZMA using Gasdermin B (Full Length+C terminal) Rabbit pAb (A25770) at 1:1000 dilution incubated overnight at 4°C.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 30 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020)
Exposure time: 1 s.
<,b>,WB samples for antibody validation are kindly provided by Dr. Feng Shao, NIBS<,/b>,