Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
ABflo 700
Alternative Names:
7B4, CD144
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
Cross-Reactivity: Human. ResearchArea: Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology Developmental Biology,Cell Adhesion,Cadherins,Tight Junctions,Cytoskeleton,Immunology Inflammation,CDs,Stem Cells,Cardiovascular. Shipping: Ice Bag
Flow cytometry: 1X10 6 HeLa cells (negative control,left)and BeWo cells (right) were surface-stained with ABflo 700 Rabbit anti-Human CD144/VE Cadherin mAb (A26373,5 µl/Test,orange line) or ABflo 700 Rabbit IgG isotype control (5 µl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
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