Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
PerCP
Alternative Names:
OtB7, SIGNR1, mSIGNR1, DC-SIGNR1, 1810030I22Rik
CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
Cross-Reactivity: Mouse. ResearchArea: Immunology Innate Immunity Macrophage / Inflamm.Immunology Cell Type Markers CD Myeloid CellsTags & Cell Markers Cell Type Markers Other Cell Types. Shipping: Ice Bag
Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo 488 Rabbit anti-Mouse CD11b mAb (A24094,5 µl/Test) and PerCP Rabbit IgG isotype control (A24204,5 µl/Test,left) or PerCP Rabbit anti-Mouse CD209b/DC-SIGNR1 mAb (A26547,5 µl/Test,right).Cells in the Monocytes gate were used for analysis.
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