PE Rabbit anti-Mouse CD140b/PDGFRbeta mAb, Monoclonal

Product Overview

• Article Name: PE Rabbit anti-Mouse CD140b/PDGFRbeta mAb, Monoclonal
• Biozol Catalog Number: ABB-A26689
• Supplier Catalog Number: A26689
• Alternative Catalog Number: ABB-A26689-2X100T,ABB-A26689-100T,ABB-A26689-5X100T
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: PE
• Alternative Names: Pdgfr, CD140b, PDGFR-1

Product Description

Enables platelet-derived growth factor-activated receptor activity and signaling receptor binding activity. Involved in several processes, including positive regulation of intracellular signal transduction, protein phosphorylation, and vasculature development. Acts upstream of or within several processes, including animal organ development, response to ceramide, and ruffle assembly. Located in cell surface, cytoplasm, and ruffle. Is expressed in several structures, including alimentary system, extraembryonic component, genitourinary system, nervous system, and sensory organ. Used to study basal ganglia calcification, infantile myofibromatosis, myeloproliferative neoplasm, and severe nonproliferative diabetic retinopathy. Human ortholog(s) of this gene implicated in basal ganglia calcification, glioblastoma, infantile myofibromatosis, myeloproliferative neoplasm (multiple), and renal cell carcinoma. Orthologous to human PDGFRB (platelet derived growth factor receptor beta).

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 123kDa
• NCBI: 18596
• UniProt: P05622
• Purity: Affinity purification
• Target: Pdgfrb

Application Notes

• Application Dilute: FC,5 µl per 10 6 cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Cardiovascular Angiogenesis Growth Factors OtherSignal Transduction Protein Phosphorylation Tyrosine Kinases Receptor Tyrosine KinasesSignal Transduction Growth Factors/Hormones PDGFMicrobiology Organism Virus RNA Virus ssRNA positive strand virus SARS CoronavirusCancer Growth factors PDGFCancer Oncoproteins/suppressors Oncoproteins Growth factor receptorsCardiovascular Atherosclerosis Vascular Inflammation Inflammatory mediatorsNeuroscience Development. Shipping: Ice Bag

Images

Flow cytometry: 1X10 6 NIH/3T3 cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 µl/Test,left) or PE Rabbit anti-Mouse CD140b/PDGFR beta mAb (A26689,5 µl/Test,right).