Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
PE
Alternative Names:
ASP, C3a, C3b, AHUS5, ARMD9, CPAMD1, HEL-S-62p
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Cross-Reactivity: Human. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Immunology Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway. Shipping: Ice Bag
Flow cytometry: 1X10 6 Jurkat cells (negative control,left) and HepG2 cells (right) were surface-stained with PE Rabbit anti-Human Complement C3 mAb (A27173,5 µl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 µl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
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