Slug Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: Slug Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A27232
• Supplier Catalog Number: A27232
• Alternative Catalog Number: ABB-A27232-20UL,ABB-A27232-1000UL,ABB-A27232-100UL,ABB-A27232-500UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: SLUG, WS2D, SLUGH, SLUGH1, SNAIL2

Product Description

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 30kDa
• NCBI: 6591
• UniProt: O43623
• Purity: Affinity purification
• Target: SNAI2

Application Notes

• Application Dilute: WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse. ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Cancer,Cell Biology Developmental Biology,Neuroscience, Cell Type Marker,Stem Cells,Neural Stem Cells. Shipping: Ice Bag

Images

Western blot analysis of various lysates using Slug Rabbit mAb (A27232) at 1:1000 dilutionincubated at room temperature for 1.5 hours.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Negative control (NC): MCF7
Exposure time: 60s.