ABflo 610 Rat anti-Mouse MHC Class II (I-A/I-E) mAb, Monoclonal

Product Overview

• Article Name: ABflo 610 Rat anti-Mouse MHC Class II (I-A/I-E) mAb, Monoclonal
• Biozol Catalog Number: ABB-A27307
• Supplier Catalog Number: A27307
• Alternative Catalog Number: ABB-A27307-2X100T,ABB-A27307-100T,ABB-A27307-5X100T
• Manufacturer: ABclonal
• Host: Rat
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: ABflo 610
• Alternative Names: Eb, Ia4, H2Eb, Ia-4, H-2Eb,IAb, Ia2, Ia-2, Abeta, H-2Ab, H2-Ab, Rmcs1, I-Abeta, Ia5, Ia-5, H-2Eb2, Iebeta2, A130038H09Rik, Ia1, H2Aa, Ia-1, H-2Aa, Aalpha, IAalpha, I-Aalpha

Product Description

Predicted to enable several functions, including MHC class II receptor activity, peptide antigen binding activity, and signaling receptor binding activity. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II. Predicted to be located in external side of plasma membrane and immunological synapse. Predicted to be part of MHC class II protein complex. Predicted to be active in late endosome membrane and lysosomal membrane. Is expressed in lung. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple), autoimmune disease (multiple), bacterial infectious disease (multiple), eye disease (multiple), and sarcoidosis (multiple). Orthologous to several human genes including HLA-DRB5 (major histocompatibility complex, class II, DR beta 5).

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 30kDa/32kDa/26kDa
• NCBI: 14969
• UniProt: P18468
• Purity: Affinity purification
• Target: MHC Class II (I-A/I-E)

Application Notes

• Application Dilute: FC,5 µl per 10 6 cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Immunology,Adaptive Immunity,MHC Class II. Shipping: Ice Bag

Images

Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo 610 Rat IgG isotype control (5 µl/Test,left) or ABflo 610 Rat anti-Mouse MHC Class II (I-A/I-E) mAb (A27307,5 µl/Test,right).