IGF2BP3 Rabbit pAb, Unconjugated, Polyclonal

Catalog Number: ABB-A2750
Article Name: IGF2BP3 Rabbit pAb, Unconjugated, Polyclonal
Biozol Catalog Number: ABB-A2750
Supplier Catalog Number: A2750
Alternative Catalog Number: ABB-A2750-20UL,ABB-A2750-100UL,ABB-A2750-500UL,ABB-A2750-1000UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: KOC, CT98, IMP3, KOC1, IMP-3, VICKZ3, IGF2BP3
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5 UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
Clonality: Polyclonal
Molecular Weight: 64kDa
NCBI: 10643
UniProt: O00425
Purity: Affinity purification
Sequence: MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGKIELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETAVVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRL
Target: IGF2BP3
Antibody Type: Primary Antibody
Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,RNA Binding,Cancer,Tumor biomarkers. Shipping: Ice Bag
Western blot analysis of various lysates using IGF2BP3 Rabbit pAb (A2750) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.