Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
ABflo 610
Alternative Names:
DX5, GPIa, CD49B
Enables amyloid-beta binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway, positive regulation of cell migration, and positive regulation of cellular component organization. Predicted to act upstream of or within cell adhesion. Located in basal part of cell and external side of plasma membrane. Is expressed in several structures, including alimentary system, brain, cardiovascular system, eye, and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including Behcets disease, artery disease (multiple), blood platelet disease (multiple), diabetes mellitus (multiple), and von Willebrands disease (multiple). Orthologous to human ITGA2 (integrin subunit alpha 2).
Cross-Reactivity: Mouse. ResearchArea: Immunology Adaptive Immunity T Cells CDSignal Transduction Cytoskeleton / ECM Cell Adhesion Integrins Alpha. Shipping: Ice Bag
Flow cytometry:1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo 488 Rabbit anti-Mouse CD161c/NK1.1 mAb (A24922,5 µl/Test) and ABflo610 Rabbit IgG isotype control (A25826,5 µl/Test,left) or ABflo 610 Rabbit anti-Mouse Integrin alpha 2/CD49b mAb (A27641,0.25µg,right).
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