ABflo 488 Rabbit anti-Human PLZF mAb, Monoclonal

Product Overview

• Article Name: ABflo 488 Rabbit anti-Human PLZF mAb, Monoclonal
• Biozol Catalog Number: ABB-A27688
• Supplier Catalog Number: A27688
• Alternative Catalog Number: ABB-A27688-5X100T,ABB-A27688-100T,ABB-A27688-2X100T
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: ABflo 488
• Alternative Names: PLZF, ZNF145

Product Description

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.

Product Properties

• Clonality: Monoclonal
• Concentration: FC (intra)
• Molecular Weight: 74kDa
• NCBI: 7704
• UniProt: Q05516
• Purity: Affinity purification
• Target: ZBTB16

Application Notes

• Application Dilute: FC (intra),5 µl per 10 6 cells in 100 µl volume
• Application Notes: Cross-Reactivity: Human. ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Cancer,Cell Biology Developmental Biology,Apoptosis,Stem Cells,Germline Stem Cells,Hematopoietic Progenitors. Shipping: Ice Bag

Images

Flow cytometry:1X10 6 Human PBMC were surface stained with APC Mouse anti-Human CD56 mAb (A26869,5 µl/Test) and then intracellularly-stained with ABflo 488 Rabbit IgG isotype control (A22069,5 µl/Test,left) or ABflo 488 Rabbit anti-Human PLZF mAb (A27688,5 µl/Test,right). Cells in the lymphocyte gate were used for analysis.