PE/Cyanine7 Armenian Hamster anti-Mouse CD3e mAb, PE/Cy7, Monoclonal

Product Overview

• Article Name: PE/Cyanine7 Armenian Hamster anti-Mouse CD3e mAb, PE/Cy7, Monoclonal
• Biozol Catalog Number: ABB-A27751
• Supplier Catalog Number: A27751
• Alternative Catalog Number: ABB-A27751-25UG,ABB-A27751-100UG
• Manufacturer: ABclonal
• Host: Hamster
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Recombinant protein of mouse CD3e.
• Conjugation: PE/Cy7
• Alternative Names: CD3, T3e, CD3epsilon

Product Description

Predicted to enable several functions, including SH3 domain binding activity, identical protein binding activity, and protein heterodimerization activity. Involved in nervous system development and positive regulation of cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell activation, positive regulation of cytokine production, and regulation of signal transduction. Located in several cellular components, including dendritic spine, external side of plasma membrane, and immunological synapse. Part of alpha-beta T cell receptor complex. Is expressed in colon and hemolymphoid system. Human ortholog(s) of this gene implicated in immunodeficiency 18. Orthologous to human CD3E (CD3e molecule).

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 21kDa
• NCBI: 12501
• UniProt: P22646
• Purity: Affinity purification
• Target: Cd3e

Application Notes

• Application Dilute: FC,0.25 µg per million cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: GO - Molecular functioni identical protein binding Source: MGI protein heterodimerization activity Source: MGI SH3 domain binding Source: MGI transmembrane signaling receptor activity Source: GO_Central Complete GO annotation on QuickGO ... GO - Biological processi adaptive immune response Source: UniProtKB-KW apoptotic signaling pathway Source: MGI cell surface receptor signaling pathway Source: MGI cerebellum development Source: ARUK-UCL dendrite development Source: ARUK-UCL lymphocyte activation Source: MGI negative regulation of gene expression Source: MGI negative regulation of smoothened signaling pathway Source: MGI negative thymic T cell selection Source: MGI positive regulation of alpha-beta T cell proliferation Source: MGI positive regulation of calcium-mediated signaling Source: MGI positive regulation of cell-cell adhesion mediated by integrin Source: BHF-UCL positive regulation of cell-matrix adhesion Source: BHF-UCL positive regulation of gene expression Source: MGI positive regulation of interferon-gamma production Source: MGI positive regulation of interleukin-2 production Source: MGI positive regulation of interleukin-4 production Source: MGI positive regulation of peptidyl-tyrosine phosphorylation Source: MGI positive regulation of T cell activation Source: MGI positive regulation of T cell anergy Source: MGI positive regulation of T cell proliferation Source: MGI positive thymic T cell selection Source: GO_Central response to nutrient Source: MGI T cell costimulation Source: MGI T cell receptor signaling pathway Source. Shipping: Ice Bag

Images

Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with PE/Cyanine7 Armenian Hamster IgG isotype control (0.25µg,left) or PE/Cyanine7 Armenian Hamster anti-Mouse CD3e mAb (A27751,0.25µg,right).