Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
PE
Alternative Names:
Cd1a, Cd1d, CD1.1, Ly-38
Enables T cell receptor binding activity and endogenous lipid antigen binding activity. Involved in NK T cell differentiation and regulation of immature T cell proliferation in thymus. Acts upstream of or within several processes, including antigen processing and presentation, exogenous lipid antigen via MHC class Ib, positive regulation of cytokine production, and positive regulation of leukocyte activation. Located in endosome, external side of plasma membrane, and lysosome. Is expressed in forebrain, intestine, jaw bone, and liver. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to human CD1D (CD1d molecule).
Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with APC Rat anti-Mouse CD45R/B220 mAb (A27570,5 µl/Test) and PE Rabbit IgG isotype control (A24172,5 µl/Test,left) or PE Rabbit anti-Mouse CD1d mAb (A27959,0.25 µg,right).
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