Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
APC
Alternative Names:
CD11C, SLEB6
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Cross-Reactivity: Human. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled Receptors Signaling to MAPK Erk,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology Inflammation,CDs,Stem Cells,Hematopoietic Progenitors. Shipping: Ice Bag
Flow cytometry:1X10 6 Human PBMC were surface-stained with PE Rabbit anti-Human/Monkey CD14 mAb (A25938,5 µl/Test) and APC Mouse IgG1 isotype control (5 µl/Test,left) or APC Mouse anti-Human CD11c mAb (A27961,5 µl/Test,right). Cells in the monocyte gate were used for analysis.
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