IGFBP3 Rabbit pAb, Unconjugated, Polyclonal

Product Overview

• Article Name: IGFBP3 Rabbit pAb, Unconjugated, Polyclonal
• Biozol Catalog Number: ABB-A27971
• Supplier Catalog Number: A27971
• Alternative Catalog Number: ABB-A27971-1000UL,ABB-A27971-100UL,ABB-A27971-20UL,ABB-A27971-500UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: IGFBP-3, IGgfbp3

Product Description

Enables fibronectin binding activity and insulin-like growth factor binding activity. Involved in osteoblast differentiation. Acts upstream of or within several processes, including positive regulation of signal transduction, regulation of glucose metabolic process, and type B pancreatic cell proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system, brain, early embryo, gonad, and limb. Human ortholog(s) of this gene implicated in several diseases, including Alzheimers disease, Turner syndrome, diabetes mellitus (multiple), prostate cancer, and transitional cell carcinoma. Orthologous to human IGFBP3 (insulin like growth factor binding protein 3).

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 32kDa
• NCBI: 16009
• UniProt: P47878
• Purity: Affinity purification
• Sequence: GAGAVGAGPVVRCEPCDARALSQCAPPPTAPACTELVREPGCGCCLTCALREGDACGVYTERCGTGLRCQPRPAEQYPLRALLNGRGFCANASAAGSLSTYLPSQPAPGNISESEEEHNAGSVESQVVPSTHRVTDSKFHPLHAKMDVIKKGHARDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYDTKGKD
• Target: Igfbp3

Application Notes

• Application Dilute: WB,1:1500 - 1:6000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse,Rat. ResearchArea: Signal Transduction,Cell Biology Developmental Biology,Apoptosis,Growth factors,Endocrine Metabolism,Endocrine and metabolic diseases,Diabetes,Obesity,Cardiovascular,Angiogenesis. Shipping: Ice Bag

Images

Western blot analysis of lysates from Mouse serum using IGFBP3 Rabbit pAb (A27971) at 1:5000 dilution incubated overnight at 4°C.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45s.