PE/Cyanine7 Rat anti-Mouse CD3 mAb, PE/Cy7, Monoclonal

Product Overview

• Article Name: PE/Cyanine7 Rat anti-Mouse CD3 mAb, PE/Cy7, Monoclonal
• Biozol Catalog Number: ABB-A28018
• Supplier Catalog Number: A28018
• Alternative Catalog Number: ABB-A28018-100UG,ABB-A28018-25UG
• Manufacturer: ABclonal
• Host: Rat
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: PE/Cy7
• Alternative Names: T3d, CD3, T3e, CD3epsilon

Product Description

Predicted to enable identical protein binding activity and transmembrane signaling receptor activity. Involved in positive thymic T cell selection. Part of alpha-beta T cell receptor complex. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in immunodeficiency 19 and severe combined immunodeficiency. Orthologous to human CD3D (CD3d molecule). Predicted to enable several functions, including SH3 domain binding activity, identical protein binding activity, and protein heterodimerization activity. Involved in nervous system development and positive regulation of cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell activation, positive regulation of cytokine production, and regulation of signal transduction. Located in several cellular components, including dendritic spine, external side of plasma membrane, and immunological synapse. Part of alpha-beta T cell receptor complex. Is expressed in colon and hemolymphoid system. Human ortholog(s) of this gene implicated in immunodeficiency 18. Orthologous to human CD3E (CD3e molecule).

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 19kDa/21kDa
• NCBI: 12500
• UniProt: P04235
• Purity: Affinity purification
• Target: CD3E/CD3D

Application Notes

• Application Dilute: FC, 0.25 µg per million cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Immunology Adaptive Immunity T Cells CDStem Cells Hematopoietic Progenitors Hematopoietic Stem Cells Human Lineage NegativeImmunology Adaptive Immunity Regulatory T Cells. Shipping: Ice Bag

Images

Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo 450 Rabbit anti-Mouse CD19 (A26192,5 µl/Test) and PE/Cyanine7 Rat IgG2b isotype control (5 µl/Test,left) or PE/Cyanine7 Rat anti-Mouse CD3 mAb (A28018,0.25 µg,right) .