Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
ABflo 647
Alternative Names:
OX40, ACT35, CD134, IMD16, TXGP1L
CD134, also known as OX40 and TNFRSF4, is a 50 kDa type I transmembrane glycoprotein. It is a member of the tumor necrosis factor receptor superfamily (TNFRSF). OX40 is expressed on activated T lymphocytes, including Th1, Th2, Th17, and Treg cell subsets. The interaction between OX40 and its ligand OX40L (TNFSF4) induces B cell proliferation and antibody secretion, and modulates primary T cell expansion and T cell survival. Furthermore, OX40 influences the size of the T cell memory pool and modulates CD4+ T cell tolerance.
Cross-Reactivity: Human. ResearchArea: Immunology Inflammation,CDs,Cytokines,NF-kB Signaling Pathway. Shipping: Ice Bag
Flowcytometry:1X10 6Human PBMC (untreated,left)andHuman PBMC (treated with 10 µg/ml PHA for 2days,right) weresurface-stainedwithABflo 647 Rabbit anti-Human CD134/OX40 mAb(A28035, 5 µl/test). Cells in the lymphocyte gate were used for analysis.
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