ABflo 647 Rabbit anti-Human CD134/OX40 mAb, Monoclonal

Catalog Number: ABB-A28035
Article Name: ABflo 647 Rabbit anti-Human CD134/OX40 mAb, Monoclonal
Biozol Catalog Number: ABB-A28035
Supplier Catalog Number: A28035
Alternative Catalog Number: ABB-A28035-5X100T,ABB-A28035-2X100T,ABB-A28035-100T
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: FC
Species Reactivity: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation: ABflo 647
Alternative Names: OX40, ACT35, CD134, IMD16, TXGP1L
CD134, also known as OX40 and TNFRSF4, is a 50 kDa type I transmembrane glycoprotein. It is a member of the tumor necrosis factor receptor superfamily (TNFRSF). OX40 is expressed on activated T lymphocytes, including Th1, Th2, Th17, and Treg cell subsets. The interaction between OX40 and its ligand OX40L (TNFSF4) induces B cell proliferation and antibody secretion, and modulates primary T cell expansion and T cell survival. Furthermore, OX40 influences the size of the T cell memory pool and modulates CD4+ T cell tolerance.
Clonality: Monoclonal
Concentration: FC
Molecular Weight: 29kDa
NCBI: 7293
UniProt: P43489
Purity: Affinity purification
Target: TNFRSF4
Application Dilute: FC,5 µl per 10 6 cells in 100 µl volume
Application Notes: Cross-Reactivity: Human. ResearchArea: Immunology Inflammation,CDs,Cytokines,NF-kB Signaling Pathway. Shipping: Ice Bag
Flowcytometry:1X10 6Human PBMC (untreated,left)andHuman PBMC (treated with 10 µg/ml PHA for 2days,right) weresurface-stainedwithABflo 647 Rabbit anti-Human CD134/OX40 mAb(A28035, 5 µl/test). Cells in the lymphocyte gate were used for analysis.