Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation:
PE
Alternative Names:
loc, B220, Cd45, L-CA, Ly-5, T200, CD45R, Lyt-4
Enables several functions, including heparan sulfate proteoglycan binding activity, heparin binding activity, and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation, positive regulation of macromolecule metabolic process, and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation, positive regulation of lymphocyte activation, and regulation of protein phosphorylation. Located in external side of plasma membrane, focal adhesion, and membrane raft. Is expressed in several structures, including 3rd branchial arch, alimentary system, cardiovascular system, hemolymphoid system, and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C, multiple sclerosis, severe combined immunodeficiency, and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).
Cross-Reactivity: Mouse. ResearchArea: Immunology,Adaptive Immunity,B Cells,CD. Shipping: Ice Bag
Flow cytometry: 1X106 C57BL/6 mouse splenocytes were surface-stained with ABflo 488 Rabbit anti-Mouse CD19 mAb (A24100,5 µl/Test) and PE Rat IgG2a isotype control (5 µl/Test,left) or PE Rat anti-Mouse CD45R/B220 mAb (A28072,0.5 µg,right).
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