Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
APC/Cy7
Alternative Names:
ARK, UFO, JTK11, Tyro7
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.
Cross-Reactivity: Human. ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology Developmental Biology,Cell Cycle,Immunology Inflammation. Shipping: Ice Bag
Flow cytometry: 1X10 6 Human PBMC were surface stained with ABflo 488 Rabbit anti-Human/Monkey CD3 mAb (A26283,5 µL/Test), ABflo 488 Rabbit anti-Human/Monkey CD19 mAb (A23008,5 µL/Test), ABflo 488 Rabbit anti-Human/Monkey CD14 mAb (A25071,5 µL/Test), ABflo 488 Mouse anti-Human CD15/SSEA-1 mAb (A26929,5 µL/Test), ABflo 450 Rabbit anti-Human CD303/BDCA-2 mAb (A27911,5 µL/Test) and APC/Cyanine7 Rabbit IgG isotype control (5 µl/Test,left) or APC/Cyanine7 Rabbit anti-Human AXL mAb (A28127,5 µl/Test,right). The CD3^CD19^CD14^CD15^ population was used for analysis.
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