PE Rabbit anti-Mouse IL-1beta mAb, Monoclonal

Product Overview

• Article Name: PE Rabbit anti-Mouse IL-1beta mAb, Monoclonal
• Biozol Catalog Number: ABB-A28240
• Supplier Catalog Number: A28240
• Alternative Catalog Number: ABB-A28240-100UG,ABB-A28240-25UG
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: PE
• Alternative Names: Il-1b, IL-1beta

Product Description

Interleukin-1beta (IL-1beta) is an important cytokine and peptide regulator primarily produced by mononuclear phagocytes. It plays a key immunomodulatory role in the activation of cellular immunity. IL-1beta is involved in various physiological processes, including hematopoiesis, nervous and endocrine system regulation, inflammatory responses, and certain anti-tumor mechanisms. However, sustained and aberrant production of IL-1 within local tissues can lead to systemic effects such as fever, inflammatory reactions, and pathological changes associated with certain diseases.

Product Properties

• Clonality: Monoclonal
• Concentration: FC (intra)
• Molecular Weight: 31 kDa
• NCBI: 16176
• UniProt: P10749
• Purity: Affinity purification
• Target: Il1b

Application Notes

• Application Dilute: FC (intra),5 µl per 10 6 cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Immunology, Innate Immunity, Cytokines, Interleukins, Cardiovascular, Atherosclerosis, Vascular Inflammation, Inflammatory mediators, Metabolism, Neuroscience. Shipping: Ice Bag

Images

Flow cytometry: 1X10 6 RAW 264.7 cells (untreated,left) and RAW 264.7 cells (treated with 100ng/ml LPS for 4h and then with 1µg/ml BFA for another 3h,right) were intracellularly-stained with PE Rabbit anti-Mouse IL-1beta mAb (A28240,5 µl/Test).