Granzyme B Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A28337
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| Article Name: | Granzyme B Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A28337 |
| Supplier Catalog Number: | A28337 |
| Alternative Catalog Number: | ABB-A28337-100UL,ABB-A28337-1000UL,ABB-A28337-20UL,ABB-A28337-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Mouse |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | GZB, CCP1, Ctla1, Ctla-1, CCP-1/C11 |
| This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. |
| Application Dilute: | WB,1:1000 - 1:3000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (1:10000),a sequential dilution method is strongly recommended to ensure |
| Application Notes: | Cross-Reactivity: Mouse. ResearchArea: Immunology & Infectious Disease. Shipping: Ice Bag |
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Western blot analysis of lysates from Mouse spleen using Granzyme B Rabbit pAb (A28337) at 1:3000 dilution incubated overnight at 4°C. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 45 s. |
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