PE Rabbit anti-Mouse CD95/FAS mAb, Monoclonal

Product Overview

• Article Name: PE Rabbit anti-Mouse CD95/FAS mAb, Monoclonal
• Biozol Catalog Number: ABB-A28357
• Supplier Catalog Number: A28357
• Alternative Catalog Number: ABB-A28357-100UG,ABB-A28357-25UG
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: PE
• Alternative Names: lpr, APO1, APT1, CD95, TNFR6, Tnfrsf6

Product Description

CD95, also known as Fas, is a approximately 45 kD type I transmembrane protein in the TNFR superfamily (TNFRSF6). CD95 was expressed in thymus, spleen, liver, heart, lung, ovary and other organs. CD95 binds ligand (FasL) to form a death-inducing signaling complex (DISC) in cells to induce apoptosis. Cd95-induced apoptosis plays an important role in development and in maintaining peripheral tolerance of the immune system.

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 37 KDa
• NCBI: 14102
• UniProt: P25446
• Purity: Affinity purification
• Target: Fas

Application Notes

• Application Dilute: FC,0.25 µg per million cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Cell biology, apoptosis, receptors, death receptors. Shipping: Ice Bag

Images

Flow cytometry:1X10 6 C57BL/6 mouse thymocytes were surface-stained with APC Rabbit anti-Mouse CD8a mAb (A27839,0.25 µg) and PE Rabbit IgG isotype control (A24172,5 µl/Test,left) or PE Rabbit anti-Mouse CD95/FAS mAb (A28357,0.25 µg,right).