Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
APC
Alternative Names:
Cd59, MACIF, MAC-IP
Predicted to enable complement binding activity. Involved in several processes, including negative regulation of angiogenesis, negative regulation of fibroblast growth factor production, and negative regulation of vascular endothelial growth factor receptor signaling pathway. Acts upstream of or within negative regulation of activation of membrane attack complex. Located in external side of plasma membrane. Is expressed in several structures, including Meckels cartilage, nervous system, neural retina, skeleton, and testis. Human ortholog(s) of this gene implicated in colorectal carcinoma and ovarian cancer. Orthologous to human CD59 (CD59 molecule (CD59 blood group)).
Flow cytometry:1X10 6 C57BL/6 mouse bone marrow cells were surface-stained with FITC anti-Mouse TER-119 mAb (A25656,0.25 µg) and APC Rabbit IgG isotype control (A24173,5 µl/Test,left) or APC Rabbit anti-Mouse CD59a mAb (A28360,0.25 µg,right).
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