ABflo 610 Rabbit anti-Mouse CD11b mAb, Monoclonal

Product Overview

• Article Name: ABflo 610 Rabbit anti-Mouse CD11b mAb, Monoclonal
• Biozol Catalog Number: ABB-A28363
• Supplier Catalog Number: A28363
• Alternative Catalog Number: ABB-A28363-100UG,ABB-A28363-50UG
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: ABflo 610
• Alternative Names: CR3, CR3A, MAC1, Cd11b, Ly-40, Mac-1, Mac-1a, CD11b/CD18, F730045J24Rik

Product Description

Enables complement component C3b binding activity, heparan sulfate proteoglycan binding activity, and heparin binding activity. Contributes to cargo receptor activity. Involved in several processes, including central nervous system development, endocytosis, and positive regulation of neuron death. Acts upstream of or within several processes, including activated T cell proliferation, leukocyte migration, and microglia development. Located in external side of plasma membrane and nucleus. Is integral component of membrane. Part of integrin alphaM-beta2 complex. Is expressed in several structures, including central nervous system, heart, lymphatic vessel, thymus, and yolk sac. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to human ITGAM (integrin subunit alpha M).

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 127 kDa
• NCBI: 16409
• UniProt: P05555
• Purity: Affinity purification
• Target: Itgam

Application Notes

• Application Dilute: FC,0.5 µg per million cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Signal Transduction,Tags & Cell Markers,Neuroscience,Stem Cells. Shipping: Ice Bag

Images

Flow cytometry: 1X10 6 C57BL/6 mouse bone marrow cells were surface-stained with ABflo 610 Rabbit IgG isotype control (A25826,5 µl/Test,left) or ABflo 610 Rabbit anti-Mouse CD11b mAb (A28363,0.5 µg,right).