ABflo 500 Rat anti-Mouse CD45R/B220 mAb, Monoclonal

Product Overview

• Article Name: ABflo 500 Rat anti-Mouse CD45R/B220 mAb, Monoclonal
• Biozol Catalog Number: ABB-A28386
• Supplier Catalog Number: A28386
• Alternative Catalog Number: ABB-A28386-100UG,ABB-A28386-50UG
• Manufacturer: ABclonal
• Host: Rat
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: ABflo 500
• Alternative Names: loc, B220, Cd45, L-CA, Ly-5, T200, CD45R, Lyt-4

Product Description

Enables several functions, including heparan sulfate proteoglycan binding activity, heparin binding activity, and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation, positive regulation of macromolecule metabolic process, and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation, positive regulation of lymphocyte activation, and regulation of protein phosphorylation. Located in external side of plasma membrane, focal adhesion, and membrane raft. Is expressed in several structures, including 3rd branchial arch, alimentary system, cardiovascular system, hemolymphoid system, and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C, multiple sclerosis, severe combined immunodeficiency, and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 130 kDa/140 kDa/144 kDa
• NCBI: 19264
• UniProt: P06800
• Purity: Affinity purification
• Target: PTPRC

Application Notes

• Application Dilute: FC,0.5 µg per million cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Immunology,Adaptive Immunity,B Cells,CD. Shipping: Ice Bag

Images

Flow cytometry:1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo 500 Rat IgG2a isotype control (5 µl/Test,left) or ABflo 500 Rat anti-Mouse CD45R/B220 mAb (A28386,0.5 µg,right).