Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
APC/Cy7
Alternative Names:
NEP, SFE, CD10, CALLA, CMT2T, SCA43
The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
Flow cytometry: 1X10 6 Daudi cells were surface-stained with APC/Cyanine7 Rabbit IgG isotype control (5 µl/Test,left) or APC/Cyanine7 Rabbit anti-Human CD10 mAb (A28464,5 µl/Test,right).
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