CDC37 Rabbit pAb, Unconjugated, Polyclonal

Product Overview

• Article Name: CDC37 Rabbit pAb, Unconjugated, Polyclonal
• Biozol Catalog Number: ABB-A2859
• Supplier Catalog Number: A2859
• Alternative Catalog Number: ABB-A2859-1000UL,ABB-A2859-500UL,ABB-A2859-20UL,ABB-A2859-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IP, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: P50CDC37, CDC37

Product Description

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 44kDa
• NCBI: 11140
• UniProt: Q16543
• Purity: Affinity purification
• Sequence: MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIK
• Target: CDC37
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:200 - 1:1000|IP,0.5µg-4µg antibody for 200µg-400µg extracts of whole cells|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse. ResearchArea: Epigenetics Nuclear Signaling,Signal Transduction,Kinase,Cell Biology Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cell Cycle,Endocrine Metabolism,Mitochondrial metabolism. Shipping: Ice Bag

Images

Western blot analysis of various lysates using CDC37 Rabbit pAb (A2859) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.