Coilin Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: Coilin Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A3483
• Supplier Catalog Number: A3483
• Alternative Catalog Number: ABB-A3483-100UL,ABB-A3483-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: CLN80, p80-coilin, Coilin

Product Description

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 63kDa
• NCBI: 8161
• UniProt: P38432
• Purity: Affinity purification
• Target: COIL

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse. ResearchArea: Epigenetics Nuclear Signaling,Neuroscience, Cell Type Marker,Neuron marker. Shipping: Ice Bag

Images

Western blot analysis of various lysates using Coilin Rabbit mAb (A3483) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90 s.