Dynein intermediate chain 1 Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: Dynein intermediate chain 1 Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A3624
• Supplier Catalog Number: A3624
• Alternative Catalog Number: ABB-A3624-100UL,ABB-A3624-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: PCD, DIC1, ICS1, CILD1, Dynein intermediate chain 1

Product Description

This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 79kDa
• NCBI: 27019
• UniProt: Q9UI46
• Purity: Affinity purification
• Target: DNAI1

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse,Rat. ResearchArea: Signal transduction,Cell biology developmental Bbiology,Cell adhesion,Cytoskeleton,Microtubules,Motor proteins,Neuroscience, Cell type marker,Neurodegenerative diseases,Neuron marker. Shipping: Ice Bag

Images

Western blot analysis of various lysates using Dynein intermediate chain 1 Rabbit mAb (A3624) at 1:1000 dilution incubated overnight at 4C.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60 s.