TNNC1 Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: TNNC1 Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A3816
• Supplier Catalog Number: A3816
• Alternative Catalog Number: ABB-A3816-20UL,ABB-A3816-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: TNC, TN-C, TNNC, CMD1Z, CMH13, TNNC1

Product Description

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase, TnT, which contains the binding site for tropomyosin, and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 18kDa
• NCBI: 7134
• UniProt: P63316
• Purity: Affinity purification
• Target: TNNC1

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse,Rat. ResearchArea: Signal Transduction,Cell Biology Developmental Biology,Cytoskeleton,Microfilaments,Cardiovascular,Heart,Contractility. Shipping: Ice Bag

Images

Western blot analysis of various lysates using TNNC1 Rabbit mAb (A3816) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.