AHR Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: AHR Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A4000
• Supplier Catalog Number: A4000
• Alternative Catalog Number: ABB-A4000-100UL,ABB-A4000-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: RP85, bHLHe76, AHR

Product Description

The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm, upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 96kDa
• NCBI: 196
• UniProt: P35869
• Purity: Affinity purification
• Target: AHR

Application Notes

• Application Dilute: WB,1:2000 - 1:6000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human. ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Cell Biology Developmental Biology,Apoptosis. Shipping: Ice Bag

Images

Western blot analysis of various lysates using AHR Rabbit mAb (A4000) at 1:6000 dilutionincubated overnight at 4°C.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Negative control (NC): Jurkat
Exposure time: 90 s.