DARPP32 Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: DARPP32 Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A4027
• Supplier Catalog Number: A4027
• Alternative Catalog Number: ABB-A4027-20UL,ABB-A4027-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: DARPP32, DARPP-32

Product Description

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 23kDa
• NCBI: 84152
• UniProt: Q9UD71
• Purity: Affinity purification
• Target: PPP1R1B

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse,Rat. ResearchArea: Protein phosphorylation,Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Kinase,Serine threonine kinases,Endocrine Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinsons Disease,Neurodegenerative Diseases Markers. Shipping: Ice Bag

Images

Western blot analysis of various lysates using DARPP32 Rabbit mAb (A4027) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.