SIGLEC5 Rabbit pAb, Unconjugated, Polyclonal

Product Overview

• Article Name: SIGLEC5 Rabbit pAb, Unconjugated, Polyclonal
• Biozol Catalog Number: ABB-A4250
• Supplier Catalog Number: A4250
• Alternative Catalog Number: ABB-A4250-20UL,ABB-A4250-100UL,ABB-A4250-500UL,ABB-A4250-1000UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: CD170, OBBP2, CD33L2, OB-BP2, SIGLEC-5, SIGLEC5

Product Description

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 61kDa
• NCBI: 8778
• UniProt: O15389
• Purity: Affinity purification
• Sequence: EKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQTITIFRNGIALEILQNTSYLPVLEGQALRLLCDA
• Target: SIGLEC5
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Immunology Inflammation,CDs. Shipping: Ice Bag

Images

Western blot analysis of lysates from Mouse spleen, using SIGLEC5 Rabbit pAb (A4250) at 1:800 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.