DDR2 Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A4296
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| Article Name: | DDR2 Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A4296 |
| Supplier Catalog Number: | A4296 |
| Alternative Catalog Number: | ABB-A4296-100UL,ABB-A4296-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | TKT, WRCN, MIG20a, NTRKR3, TYRO10, DDR2 |
| This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. |
| Application Dilute: | WB,1:1000 - 1:6000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Signal Transduction,Kinase,Tyrosine kinases,Immunology Inflammation,CDs,Neuroscience,Cardiovascular,Heart,Cardiogenesis. Shipping: Ice Bag |
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Western blot analysis of various lysates using DDR2 Rabbit mAb (A4296) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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