Peroxiredoxin 2 (PRDX2) Rabbit mAb, Unconjugated

Product Overview

• Article Name: Peroxiredoxin 2 (PRDX2) Rabbit mAb, Unconjugated
• Biozol Catalog Number: ABB-A4308
• Supplier Catalog Number: A4308
• Alternative Catalog Number: ABB-A4308-100UL, ABB-A4308-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, TDPX1, NKEF-B, HEL-S-2a, Peroxiredoxin 2 (PRDX2)

Product Description

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Product Properties

• Molecular Weight: 22kDa
• NCBI: 7001
• UniProt: P32119
• Purity: Affinity purification
• Target: PRDX2

Application Notes

• Application Dilute: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Cancer,Cell Biology Developmental Biology,Endocrine Metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease.

Images

Western blot analysis of various lysates using Peroxiredoxin 2 (PRDX2) (PRDX2) Rabbit mAb (A4308) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.