Calcineurin A Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: Calcineurin A Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A4346
• Supplier Catalog Number: A4346
• Alternative Catalog Number: ABB-A4346-100UL,ABB-A4346-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: CALN, CCN1, CNA1, CALNA, DEE91, IECEE, PPP2B, ACCIID, CALNA1, IECEE1, Calcineurin A

Product Description

Enables several functions, including ATPase binding activity, calmodulin binding activity, and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade, peptidyl-serine dephosphorylation, and response to calcium ion. Located in several cellular components, including cytosol, dendritic spine, and nucleoplasm. Part of calcineurin complex. Colocalizes with cytoplasmic side of plasma membrane. Implicated in developmental and epileptic encephalopathy 91. Biomarker of focal segmental glomerulosclerosis and schizophrenia.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 59 kDa
• NCBI: 5530
• UniProt: Q08209
• Purity: Affinity purification
• Target: PPP3CA

Application Notes

• Application Dilute: WB,1:1000 - 1:6000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology Developmental Biology,Cytoskeleton,Actins,Immunology Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Neurodegenerative Diseases. Shipping: Ice Bag

Images

Western blot analysis of various lysates using Calcineurin A Rabbit mAb (A4346) at 1:4000 dilution incubated at room temperature for 1.5 hours.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45 s.