TRIOBP Rabbit pAb, Unconjugated, Polyclonal

Product Overview

• Article Name: TRIOBP Rabbit pAb, Unconjugated, Polyclonal
• Biozol Catalog Number: ABB-A4485
• Supplier Catalog Number: A4485
• Alternative Catalog Number: ABB-A4485-100UL,ABB-A4485-20UL,ABB-A4485-1000UL,ABB-A4485-500UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC-P, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: TARA, TAP68, DFNB28, dJ37E16.4, HRIHFB2122, TRIOBP

Product Description

This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).

Product Properties

• Clonality: Polyclonal
• Molecular Weight: 261kDa
• NCBI: 11078
• UniProt: Q9H2D6
• Purity: Affinity purification
• Sequence: DVTKLSDSNKENALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPARTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLS
• Target: TRIOBP
• Antibody Type: Primary Antibody

Application Notes

• Application Dilute: WB,1:500 - 1:2000|IHC-P,1:50 - 1:200|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse. ResearchArea: Signal Transduction,Cell Biology Developmental Biology,Cytoskeleton,Microfilaments,Neuroscience. Shipping: Ice Bag

Images

Western blot analysis of various lysates using TRIOBP Rabbit pAb (A4485) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 15s.