GSR Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: GSR Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A4566
• Supplier Catalog Number: A4566
• Alternative Catalog Number: ABB-A4566-100UL,ABB-A4566-20UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: GR, GSRD, HEL-75, HEL-S-122m, GSR

Product Description

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 56kDa
• NCBI: 2936
• UniProt: P00390
• Purity: Affinity purification
• Target: GSR

Application Notes

• Application Dilute: WB,1:1000 - 1:6000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Cancer,Signal Transduction,Cell Biology Developmental Biology,Endocrine Metabolism,Mitochondrial metabolism,Mitochondrial markers. Shipping: Ice Bag

Images

Western blot analysis of various lysates using GSR Rabbit mAb (A4566) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.