Dopamine Receptor D3 (DRD3) Rabbit mAb, Unconjugated, Monoclonal

Product Overview

• Article Name: Dopamine Receptor D3 (DRD3) Rabbit mAb, Unconjugated, Monoclonal
• Biozol Catalog Number: ABB-A4587
• Supplier Catalog Number: A4587
• Alternative Catalog Number: ABB-A4587-20UL,ABB-A4587-100UL
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Conjugation: Unconjugated
• Alternative Names: D3DR, ETM1, FET1, Dopamine Receptor D3 (DRD3)

Product Description

This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 44kDa
• NCBI: 1814
• UniProt: P35462
• Purity: Affinity purification
• Target: DRD3

Application Notes

• Application Dilute: WB,1:1000 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Neuroscience. Shipping: Ice Bag

Images

Western blot analysis of various lysates using Dopamine Receptor D3 (DRD3) Rabbit mAb (A4587) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 3s.