RUNX1/2/3 Rabbit mAb, Unconjugated, Monoclonal
Catalog Number:
ABB-A5115
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| Article Name: | RUNX1/2/3 Rabbit mAb, Unconjugated, Monoclonal |
| Biozol Catalog Number: | ABB-A5115 |
| Supplier Catalog Number: | A5115 |
| Alternative Catalog Number: | ABB-A5115-100UL,ABB-A5115-20UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha, RUNX1/2/3 |
| Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Application Dilute: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse. ResearchArea: Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Hematopoietic Progenitors,Hippo Signaling Pathway,Neuroscience,Protein phosphorylation,Stem Cells,Transcription Factors. Shipping: Ice Bag |
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Western blot analysis of various lysates using RUNX1/2/3 Rabbit mAb (A5115) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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